Life science chemistry
From hit identification through lead optimisation, scale-up and metabolite production.
Nuvisan's life science chemistry platform supports clients with comprehensive, integrated services spanning drug design, synthesis, microbiological chemistry, purification and logistics. Our team of 100 scientists and lab professionals applies deep expertise and state-of-the-art technologies to accelerate your discovery endeavours. We tailor every solution to your project's needs – backed by a secure digital infrastructure and flexible global logistics.
Leaders in medicinal chemistry and digital technology
Nuvisan combines medicinal chemistry expertise with cutting-edge digital technologies to accelerate early drug design. Data science is deeply embedded in our workflows, driving smarter design strategies and informing decision-making. With tens of thousands of in-house building blocks, our scientists rapidly enumerate and screen virtual compound libraries to identify unique and tractable molecular designs. Your hit-to-lead and lead optimisation projects benefit from our team of medicinal chemists and computational scientists with decades of combined experience in big pharma.
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End-to-end chemistry solutions from milligrams to kilograms
Our team provides end-to-end chemistry solutions, synthesising small molecules from milligrams to kilograms and supporting advanced modalities including PROTACs, ADCs and peptides. With advanced purification techniques and physicochemical characterisation, we can ensure each compound meets stringent quality and property requirements. From late-stage chemistry and direct-to-biology (D2B) approaches to scalable synthesis, we deliver flexible, tailored chemistry services to support each stage of your discovery journey.
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Over 60 years of expertise in microbial biotransformations, fermentation and protein production
Nuvisan's microbiological chemistry services leverage decades of expertise in microbial biotransformation, fermentation and large-scale protein/plasmid production to support pharmaceutical R&D. Our advanced biooxidation toolbox includes over 3,000 wild-type strains and CYP variants, enabling efficient screening and synthesis of oxidative drug metabolites
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We scale up processes from milligram to gram quantities using 1–100 L fermenters, with integrated purification and analytics to help ensure your compounds achieve exact specifications. From metabolite discovery to preparative biotransformations, we offer tailored microbiological solutions for complex chemical challenges.
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Advanced separation technologies and structural characterisation for drug discovery
Our chemists provide advanced purification and compound characterisation services tailored to the demands of modern drug discovery. Our separation technologies lab delivers precise chiral and achiral separations – from milligrams to kilograms – using HPLC, UPLC and supercritical fluid chromatography (SFC).
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Equipped with cryo-probe NMR and high-resolution mass spectrometry capabilities, your structures can be elucidated quickly and accurately. Whether investigating small molecules, peptides other modalities, our capabilities enable the speed, accuracy and insight needed to advance your R&D projects.
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Fast, compliant and traceable compound handling throughout your discovery projects
Nuvisan provides integrated logistics services designed to make sure your compounds are handled efficiently, securely and in full regulatory compliance. We manage and securely store over 40,000 building blocks, including many non-commercial compounds. Our experienced team coordinates international shipments with full regulatory compliance – including dangerous goods handling and export/import documentation.
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