Chemistry is central to almost all aspects of modern drug discovery. Nuvisan’s life science chemistry platform supports clients with comprehensive, integrated services spanning drug design, synthesis, microbiological chemistry, purification, analytics and logistics. From early hit identification through lead optimisation, scale-up and metabolite production, our team of over 100 scientists and lab professionals applies deep expertise and state-of-the-art technologies to accelerate your discovery endeavours. Whether crafting complex small molecules, conducting biotransformations or delivering high-purity and thoroughly characterized compounds, we tailor every solution to your project’s needs. Backed by a secure digital infrastructure and flexible global logistics, our team of experts is dedicated to serving all your life science chemistry needs.
Nuvisan combines medicinal chemistry expertise with cutting-edge digital technologies to accelerate early drug design. Data science is deeply embedded in our workflows, driving smarter design strategies and informing decision-making. With tens of thousands of in-house building blocks, our scientists rapidly enumerate and screen virtual compound libraries to identify unique and tractable molecular designs. Your hit-to-lead and lead optimization projects will benefit from collaborating with our team of medicinal chemists and computational scientists, who offer decades of joint experience in big pharma. We know how to deliver chemical matter ready to advance into the clinic.
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Our team provides end-to-end chemistry solutions, synthesising small molecules in milligrams to kilograms while supporting advanced modalities like PROTACs, ADCs and peptides. Your chemistry benefits from standard route scouting and optimisation activities as well as innovative technologies. With advanced purification techniques and physicochemical characterisation, we help ensure each compound meets stringent quality requirements and has the properties demanded by your drug discovery programs. We specialise in building block synthesis, toxicological batches and customised processes for complex targets. From late-stage chemistry and direct-to-biology approaches to scalable synthesis, our tailored chemistry services support each stage of your discovery journey.
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Nuvisan’s microbiological chemistry services leverage over 60 years of expertise in microbial biotransformation, fermentation and large-scale production to support pharmaceutical R&D. Our advanced biooxidation toolbox includes over 3,000 wild-type strains and CYP variants, enabling efficient screening and synthesis of oxidative drug metabolites. We scale up processes from milligram to gram quantities using 1–100L fermenters, with integrated purification and analytics to help ensure your compounds achieve exact specifications. From metabolite discovery to preparative biotransformations, our tailored microbiological solutions help solve complex chemical challenges
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Our chemists provide advanced purification and compound characterisation services tailored to the demands of modern drug discovery. Our separation technologies lab delivers precise chiral and achiral separations – from milligrams to kilograms – using HPLC, UPLC and supercritical fluid chromatography (SFC). Equipped with cryo-probe NMR and high-resolution mass spectrometry capabilities, we help elucidate your structures quickly and accurately. Whether we’re investigating small molecules, peptides or complex modalities, our purification and analytical capabilities enable the speed, accuracy and insight needed to advance your R&D projects.
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Nuvisan provides integrated logistics services to help ensure fast, compliant and traceable compound handling throughout your discovery projects. We manage and securely store over 40,000 building blocks including a multitude of non-commercial compounds. Automated weighing, barcoded tracking and TECAN-based plate- and vial-formatting support high-throughput, ready-to-use delivery. Our experienced team coordinates international shipments with full regulatory compliance, including dangerous goods handling and export/import documentation. Whether managing stock solutions, building blocks or custom libraries, our logistics operations team helps ensure reliable, efficient support tailored to your project’s needs.
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